5-Chloropyrimidin-2-amine
نویسندگان
چکیده
The complete mol-ecule of the title compound, C(4)H(3)ClN(3), is generated by crystallographic mirror symmetry, with the Cl atom, one N atom and two C atoms lying on the reflecting plane. In the crystal structure, inter-molecular N-H⋯N hydrogen bonds link the mol-ecules into chains propagating in [100].
منابع مشابه
5-Bromo-2-chloropyrimidin-4-amine
In the title compound, C4H3BrClN3, the pyrimidine ring is essentially planar (r.m.s. deviation from the plane = 0.087 Å). In the crystal, pairs of N-H⋯N hydrogen bonds connect the mol-ecules into inversion dimers; these are connected by further N-H⋯N hydrogen bonds into a two-dimensional framework parallel to the bc plane.
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In the title compound, C(13)H(12)ClN(5), which is a derivative of the anti-tumor agent pazopanib {systematic name: 5-[[4-[(2,3-di-methyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzolsulfonamide}, the indazole and pyrim-idine fragments form a dihedral angle of 62.63 (5)°. In the crystal, pairs of mol-ecules related by twofold rotational symmetry are linked into dimers through ...
متن کاملN-(2-Chloropyrimidin-4-yl)-2-methyl-2H-indazol-6-amine methanol monosolvate
In the title compound, C(12)H(10)ClN(5)·CH(3)OH, the indazole ring system and the pyrimidine ring make a dihedral angle of 23.86 (4)°. In the crystal, the components are linked by N-H⋯O and O-H⋯N hydrogen bonds into chains propagated in [010]. Inter-molecular π-π inter-actions [centroid-centroid distances = 3.6404 (9), 3.6725 (9) and 3.4566 (9) Å] between the rings of neighbouring chains also s...
متن کامل2-Chloropyrimidin-4-amine
In the title pyrimidine derivative, C(4)H(4)ClN(3), the 2-chloro and 4-amino substituents almost lie in the mean plane of the pyrimidine ring, with deviations of 0.003 (1) Å for the Cl atom, and 0.020 (1) Å for the N atom. In the crystal, molecules are linked via pairs of N-H⋯N hydrogen bonds, forming inversion dimers. These dimers are further linked via N-H⋯N hydrogen bonds, forming an undulat...
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